Effekte von Leitlinien

Archiv für Juni 2009

Is physician adherence to prescription guidelines a general trait of health care practices or dependent on drug type?-A multilevel logistic regression analysis in South Sweden.

Montag, 08. Juni 2009

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Is physician adherence to prescription guidelines a general trait of health care practices or dependent on drug type?-A multilevel logistic regression analysis in South Sweden.

Pharmacoepidemiol Drug Saf. 2009 May 12;

Authors: Ohlsson H, Merlo J

PURPOSE: Therapeutic traditions at health care practices (HCPs) influence physicians’ adherence to prescription guidelines for specific drugs, however, it is not known if such traditions affect all kinds of prescriptions or only specific types of drug. Our goal was to determine whether adherence to prescription guidelines is a common trait of HCPs or dependent on drug type. METHODS: We fitted separate multi-level logistic regression models to all patients in the Skåne region who received a prescription for a statin drug (ATC: C10AA, n = 6232), an agent acting on the renin-angiotensin system (ATC: C09, n = 7222) or a proton pump inhibitor (ATC: A02BC, n = 11 563) at 198 HCPs from July 2006 to December 2006. RESULTS: There was a high clustering of adherence to prescription guidelines at HCPs for the different drug types (MOR(agents acting on the renin-angiotensin system) = 4.72 [95% CI: 3.90-5.92], MOR(Statins) = 2.71 [95% CI: 2.23-3.39] and MOR(Proton pump inhibitors) = 2.16 [95% CI: 1.95-2.45]). Compared with HCPs with low adherence to guidelines in two drug types, those HCPs with the highest level of adherence for these two drug types also showed a higher probability of adherence for the third drug type. CONCLUSION: Physicians’ decisions to follow prescription guidelines seem to be influenced by therapeutic traditions at the HCP. Moreover, these therapeutic traditions seem to affect all kinds of prescriptions. This information can be used as basis for interventions to support rational and cost-effective medication use. Copyright (c) 2009 John Wiley & Sons, Ltd.

PMID: 19437457 [PubMed - as supplied by publisher]

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The importance of drinking frequency in evaluating individuals’ drinking patterns: implications for the development of national drinking guidelines.

Montag, 08. Juni 2009

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The importance of drinking frequency in evaluating individuals’ drinking patterns: implications for the development of national drinking guidelines.

Addiction. 2009 May 11;

Authors: Paradis C, Demers A, Picard E, Graham K

ABSTRACT Aims This paper examines the relationship between frequency of drinking, usual daily consumption and frequency of binge drinking, taking into consideration possible age and gender differences. Participants and design Subjects were 10 466 current drinkers (5743 women and 4723 men) aged between 18 and 76 years, who participated in the GENACIS Canada (GENder Alcohol and Culture: an International Study) study. Setting Canada. Measurements The independent variable was the annual drinking frequency. The dependent variables were the usual daily quantity consumed, annual, monthly and weekly frequency of binge drinking (five drinks or more on one occasion). Findings Logistic regressions show (i) that those who drink less than once a week are less likely than weekly drinkers to take more than two drinks when they do drink; (ii) that the usual daily quantity consumed by weekly drinkers is not related to their frequency of drinking; but that (iii) the risk and frequency of binge drinking increase with the frequency of drinking. Conclusions Given that risk and frequency of binge drinking among Canadians increases with their frequency of drinking, any public recommendation to drink moderately should be made with great caution.

PMID: 19438417 [PubMed - as supplied by publisher]

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Adherence to 2005 Dietary Guidelines for Americans is associated with a reduced progression of coronary artery atherosclerosis in women with established coronary artery disease.

Montag, 08. Juni 2009

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Adherence to 2005 Dietary Guidelines for Americans is associated with a reduced progression of coronary artery atherosclerosis in women with established coronary artery disease.

Am J Clin Nutr. 2009 May 13;

Authors: Imamura F, Jacques PF, Herrington DM, Dallal GE, Lichtenstein AH

BACKGROUND: A premise of the 2005 Dietary Guidelines for Americans (DGA) is chronic disease prevention. OBJECTIVE: The goal was to determine whether a diet meeting the DGA is associated with less atherosclerotic lesion progression. DESIGN: We used the data from 224 postmenopausal women with established coronary artery disease enrolled in the Estrogen Replacement and Atherosclerosis Study. Atherosclerosis progression was defined by repeated measures of quantitative angiography over a 3-y period. Adherence to the key DGA recommendations was measured by using the DGA Adherence Index (DGAI; possible range: 0-20), with each component weighted equally, and the modified DGAI score (wDGAI; possible range: -0.19-0.51), with each component weighted based on its relation to atherosclerosis progression. Mixed-model regression analyses were performed to assess the association between diet and atherosclerosis progression. RESULTS: No women consumed a diet meeting all of the DGA recommendations. The mean (range) of the DGAI score was 14.1 (8.0-19.0). DGAI was not associated with atherosclerosis progression (P = 0.44), whereas wDGAI was inversely associated; a 1-SD difference in wDGAI was related to 0.049-mm less narrowing of the coronary arteries (SE = 0.017, P = 0.004). CONCLUSIONS: In postmenopausal women with established heart disease, under the assumption that all DGA recommendations are similarly effective, overall adherence was not associated with atherosclerosis progression. However, assigning differential weights to the DGA recommendations, the adherence was significantly associated with slower atherosclerosis progression. Assuming equity of associations between all dietary recommendations and disease outcomes is a limitation to accurately examine the effectiveness of the DGA.

PMID: 19439455 [PubMed - as supplied by publisher]

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Impact of guidelines for endoscopy in patients with Barrett’s esophagus: A multifaceted interventional study.

Montag, 08. Juni 2009

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Impact of guidelines for endoscopy in patients with Barrett's esophagus: A multifaceted interventional study.

Gastroenterol Clin Biol. 2009 May 12;

Authors: Amamra N, Touzet S, Colin C, Ponchon T

OBJECTIVE: To evaluate the impact of a multifaceted interventional program on the compliance of hepatogastroenterologists with guidelines for Barrett's esophagus. DESIGN: In both 2002 and 2005, anonymous postal surveys were sent out, involving eight criteria pertaining to three main areas to assess compliance, to 245 hepatogastroenterologists based in private and public hospitals, and in the community, in a specific region of France. The multifaceted intervention was based on reminders, conferences, postal campaigns and esophageal mapping. Main outcome measures were based on biopsies for diagnosis, surveillance intervals and management of patients with high-grade dysplasia. RESULTS: In 2002 and 2005, survey response rates were 81.6 and 73.9%, respectively. In terms of diagnosis, compliance with the systematic performance of biopsies increased from 26.5 to 59.9% (p<0.01) and, with follow-up, from 41.0 to 52.0%, respectively (p<0.02). Management of high-grade dysplasia increased from 16.0 to 24.3% (p<0.01). Total compliance (with all criteria) was achieved by 5.0% of hepatogastroenterologists in 2002 and by 10.7% in 2005 (p<0.01). CONCLUSION: The present study suggests that a multifaceted interventional program can dramatically improve physician compliance with the guidelines for Barrett's esophagus. For this reason, we recommend that national scientific societies disseminate their guidelines through targeted activity to ensure that they are followed by hepatogastroenterologists.

PMID: 19443156 [PubMed - as supplied by publisher]

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“Guidelines” for guideline implementation.

Montag, 08. Juni 2009

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"Guidelines" for guideline implementation.

J Pediatr. 2009 Jun;154(6):784-5

Authors: Brown HJ, Miles PV

PMID: 19446094 [PubMed - indexed for MEDLINE]

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Seventeen years of asthma guidelines: why hasn’t the outcome improved for children?

Montag, 08. Juni 2009

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Seventeen years of asthma guidelines: why hasn’t the outcome improved for children?

J Pediatr. 2009 Jun;154(6):786-8

Authors: Weinberger M

PMID: 19446095 [PubMed - indexed for MEDLINE]

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ED Information Systems: a guideline for successful implementation.

Montag, 08. Juni 2009

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ED Information Systems: a guideline for successful implementation.

J Emerg Nurs. 2009 Jun;35(3):237-8

Authors: Conn S, Shaw J, Matthews J, Wier S, Coughlin-Shuler B

PMID: 19446131 [PubMed - in process]

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The guideline “consultation psychiatry” of the Netherlands Psychiatric Association.

Montag, 08. Juni 2009

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The guideline “consultation psychiatry” of the Netherlands Psychiatric Association.

J Psychosom Res. 2009 Jun;66(6):531-5

Authors: Leentjens AF, Boenink AD, Sno HN, Strack van Schijndel RJ, van Croonenborg JJ, van Everdingen JJ, van der Feltz-Cornelis CM, van der Laan NC, van Marwijk H, van Os TW,

BACKGROUND: In 2008, the Netherlands Psychiatric Association authorized a guideline “consultation psychiatry.” AIM: To set a standard for psychiatric consultations in nonpsychiatric settings. The main objective of the guideline is to answer three questions: Is psychiatric consultation effective and, if so, which forms are most effective? How should a psychiatric consultations be performed? What increases adherence to recommendations given by the consulting psychiatrist? METHOD: Systematic literature review. RESULTS: Both in general practice and in hospital settings psychiatric consultation is effective. In primary care, the effectiveness of psychiatric consultation is almost exclusively studied in the setting of “collaborative care.” Procedural guidance is given on how to perform a psychiatric consultation. In this guidance, psychiatric consultation is explicitly looked upon as a complex activity that requires a broad frame of reference and adequate medical and pharmacological expertise and experience and one that should be performed by doctors. Investing in a good relation with the general practitioner, and the use of a “consultation letter” increased efficacy in general practice. In the hospital setting, investing in liaison activities and an active psychiatric follow-up of consultations increased adherence to advice. CONCLUSION: Psychiatric consultations are effective and constitute a useful contribution to the patients’ treatment. With setting a standard consultations will become more transparent and checkable. It is hoped that this will increase the quality of consultation psychiatry.

PMID: 19446712 [PubMed - in process]

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Single-item and multiple-item measures of adherence to public health behavior guidelines were incongruent.

Montag, 08. Juni 2009

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Single-item and multiple-item measures of adherence to public health behavior guidelines were incongruent.

J Clin Epidemiol. 2009 May 14;

Authors: van Keulen HM, Mesters I, van Mechelen W, de Vries H

OBJECTIVE: Physical activity (PA) and fruit and vegetable consumption may prevent or delay the development of hypertension and cardiovascular diseases. We examined adherence rates to single and combinations of Dutch public health guidelines for these behaviors by comparing and combining two self-report measurements. STUDY DESIGN AND SETTING: The behaviors of 2,568 Dutch participants aged 45-70 years were measured using one item and multiple items. Patients were classified as meeting or not meeting a guideline using both measurements separately and combined. RESULTS: Substantially more participants met guidelines when measured with multiple items than when measured with one item, with differences of 21-39%. Combined measurements resulted in fewer participants meeting guidelines than multiple-item measurements used alone. Combined measurements showed that 17%, 12%, and 34% of participants met the guidelines for fruit and vegetable consumption and PA, respectively; only 3% met all three guidelines. Sociodemographic variables explained less than 4% of the variance of congruency between single- and multiple-item measurements. CONCLUSION: When assessing adherence rates, the level appears dependent on the method of self-report chosen. Hence, more research must analyze which adherence measurement will result in valid responses and which variables are associated with congruency between single- and multiple-item measurements.

PMID: 19447006 [PubMed - as supplied by publisher]

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An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spondylolisthesis.

Montag, 08. Juni 2009

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An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spondylolisthesis.

Spine J. 2009 May 15;

Authors: Watters WC, Bono CM, Gilbert TJ, Kreiner DS, Mazanec DJ, Shaffer WO, Baisden J, Easa JE, Fernand R, Ghiselli G, Heggeness MH, Mendel RC, O'Neill C, Reitman CA, Resnick DK, Summers JT, Timmons RB, Toton JF

BACKGROUND CONTEXT: The objective of the North American Spine Society (NASS) evidence-based clinical guideline on the diagnosis and treatment of degenerative lumbar spondylolisthesis is to provide evidence-based recommendations on key clinical questions concerning the diagnosis and treatment of degenerative lumbar spondylolisthesis. The guideline is intended to address these questions based on the highest quality clinical literature available on this subject as of January 2007. The goal of the guideline recommendations is to assist the practitioner in delivering optimum, efficacious treatment of and functional recovery from this common disorder. PURPOSE: To provide an evidence-based, educational tool to assist spine care providers in improving the quality and efficiency of care delivered to patients with degenerative lumbar spondylolisthesis. STUDY DESIGN: Systematic review and evidence-based clinical guideline. METHODS: This report is from the Degenerative Lumbar Spondylolisthesis Work Group of the NASS Evidence-Based Clinical Guideline Development Committee. The work group was comprised of multidisciplinary spine care specialists, all of whom were trained in the principles of evidence-based analysis. Each member participated in the development of a series of clinical questions to be addressed by the group. The final questions agreed on by the group are the subject of this report. A literature search addressing each question and using a specific search protocol was performed on English language references found in MEDLINE, EMBASE (Drugs and Pharmacology) and four additional, evidence-based, databases. The relevant literature was then independently rated by at least three reviewers using the NASS-adopted standardized levels of evidence. An evidentiary table was created for each of the questions. Final grades of recommendation for the answer to each clinical question were arrived at via face-to-face meetings among members of the work group using standardized grades of recommendation. When Level I-IV evidence was insufficient to support a recommendation to answer a specific clinical question, expert consensus was arrived at by the work group through the modified nominal group technique and is clearly identified as such in the guideline. RESULTS: Nineteen clinical questions were formulated, addressing issues of prognosis, diagnosis, and treatment of degenerative lumbar spondylolisthesis. The answers to these 19 clinical questions are summarized in this document. The respective recommendations were graded by the strength of the supporting literature that was stratified by levels of evidence. CONCLUSIONS: A clinical guideline for degenerative lumbar spondylolisthesis has been created using the techniques of evidence-based medicine and using the best available evidence as a tool to aid practitioners involved with the care of this condition. The entire guideline document, including the evidentiary tables, suggestions for future research, and all references, is available electronically at the NASS Web site (www.spine.org) and will remain updated on a timely schedule.

PMID: 19447684 [PubMed - as supplied by publisher]

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